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Biologically relevant motifs

WebApr 21, 2024 · The fact that these motifs represent many of the known functional components of gammaproteobacterial oriC sequences further supports the finding that … WebSep 10, 2014 · Biologically relevant linear motifs often exhibit a statistical significance that lies in or near the twilight zone (i.e. where there is a non-negligible probability to observe a random motif) . This difficulty begs for a better understanding and characterization of motif statistical significance [2] , [18] , and calls for alternative approaches.

Frequent subgraph mining for biologically meaningful …

WebThis can be achieved by using macrocyclization to constrain peptides into their unique and bioactive conformations. Macrocyclic-based designs of biologically relevant peptides may be informed by the patterns of hydrogen bonding observed in X-ray crystal structures. Covalent surrogates of hydrogen bonds reduce entropy by destabilizing unfolded ... WebMar 24, 2024 · Biological motives are the driving force behind goal-oriented behaviors that result from an individual's physiological state. Some examples of biological motives are … cycloplegics and mydriatics https://ciclosclemente.com

A Feature-Based Approach to Modeling Protein–DNA Interactions

WebNov 4, 2005 · The algorithm presented here represents an attempt to extract biologically relevant motifs based on sequence information from large-scale mass spectrometry–based data sets, and is meant to serve ... WebMar 16, 2024 · Fig. 5: Scope of diarylation of biologically relevant motif coupled alkynes and synthetic applications. All reactions are carried out on a 0.2 mmol scale. All the compounds are isolated as a ... WebDec 23, 2024 · Jun Yang, Federico Ariel, Dong Wang, Plant long non-coding RNAs: biologically relevant and mechanistically intriguing, Journal of Experimental Botany, Volume 74, Issue 7, 9 April 2024, ... (IPS1), had a 23-nt motif complementary to miR399 and functioned as the target mimic of miR399, sequestering miRNA399 away from its … cyclopithecus

(PDF) ELM - The database of eukaryotic linear motifs

Category:Representation learning of genomic sequence motifs with ... - PLOS

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Biologically relevant motifs

Frequent subgraph mining for biologically …

WebMay 14, 2024 · Identification of biologically relevant motifs in proteins is a long-standing problem in bioinformatics, especially when considering distantly related proteins where … WebSep 6, 2012 · This highlights a caveat in predicting expression from motifs; while we can identify biologically relevant motifs, this type of analysis only suggests a subset of …

Biologically relevant motifs

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WebNov 21, 2011 · The motif discovery portion of the ELM resource has added conservation, and structural attributes have been incorporated to aid users to discriminate biologically relevant motifs from ... WebMay 1, 2008 · The motif discovery portion of the ELM resource has added conservation, and structural attributes have been incorporated to aid users to discriminate biologically relevant motifs from stochastically occurring non-functional instances.

WebJul 7, 2009 · A unique motif GX{P}[LMQ]X{P}XX{P}X{CIMPVW} was identified as a sufficient condition for peptide binding to Ydj1p. Yeast proteome screen revealed that the motif is biologically relevant and could be observed in many proteins involved in cochaperone activity, with Ydj1p and others involved in critical cellular events. WebJan 11, 2024 · We show that LncLOOM is capable of identifying specific, biologically relevant motifs which are conserved throughout vertebrates and beyond in lncRNAs …

WebBiological motion is motion that comes from actions of a biological organism. Humans and animals are able to understand those actions through experience, identification, and … WebInteractions between protomers are illustrated on the basis of oligomeric structures of each AAA+ subgroup. The possible role of conserved motifs in the nucleotide binding pocket …

WebNov 1, 2004 · We show that the module cores, the parts with the highest intramodular connectivity, are biologically relevant components of the networks. These constituents correlate only weakly with other levels of organization. ... In the case of the 5' motifs, the statistic measures the number of regulatory motifs common to at least more than half of …

cycloplegic mechanism of actionWebAn important aspect is that under normal cellular concentrations, biologically relevant motifs will generally outcompete lower affinity off-target instances 38 (the implications for motif definitions based purely on … cyclophyllidean tapewormsWebJul 7, 2009 · A unique motif GX{P}[LMQ]X{P}XX{P}X{CIMPVW} was identified as a sufficient condition for peptide binding to Ydj1p. Yeast proteome screen revealed that the … cycloplegic refraction slideshareWebAug 22, 2008 · Having chosen biologically relevant motif MHG p-value thresholds, we next compared the KMM motifs found by our motif finder for the TF-condition sets with the motifs published by MacIsaac et al. . For each TF-condition set, we allowed the motif finder to output up to five unique motifs. Only those that passed their sets' bin threshold were ... cyclophyllum coprosmoidesWebSep 9, 2024 · Crosslinking and immunoprecipitation (CLIP) is a method used to identify in vivo RNA–protein binding sites on a transcriptome-wide scale. With the increasing amounts of available data for RNA-binding proteins (RBPs), it is important to understand to what degree the enriched motifs specify the RNA-binding profiles of RBPs in cells. We … cyclopiteWebJul 1, 2024 · Studies demonstrating their existence in the human genome and role in gene regulation are now shining light on their biological relevance. Herein, we review the … cyclop junctionsWebFeb 7, 2008 · We conclude that many biologically relevant motifs appear heterogeneously distributed in the promoter region of genes, and therefore, that non-uniformity is a good indicator of biological relevance and can be used to complement over-representation tests commonly used. In this article we present the results obtained for the S. cerevisiae data … cycloplegic mydriatics