WebJul 1, 2002 · 1996a; Molecular cloning of the Haemophilus influenzae gmhA ( lpcA ) gene encoding a phosphoheptose isomerase required for lipooligosaccharide biosynthesis. J Bacteriol 178: 3339– 3341 [Google Scholar] WebThe present study encompasses exploring inhibitors against phosphoheptose isomerase (GmhA) of Leptospira, which is vital for lipopolysaccharide (LPS) biosynthesis and is identified as a common drug target through the subtractive genomic approach. GmhA model was built in Modeller 9v7.
Recombinant Escherichia coli Phosphoheptose isomerase(gmhA) …
WebThe isomerization of sedoheptulose 7-phosphate, into a phosphosugar presumed to be D-glycero-D-mannoheptose 7-phosphate, was detected in enzyme reactions with cell extracts of E. coli lpcA + and of lpcA mutants containing the recombinant lpcA gene [1]. WebLa glucosa-6-fosfat isomerasa , (en anglès: Glucose-6-phosphate isomerase o alternativament coneguda com a phosphoglucose isomerase o phosphohexose isomerase) és un enzim que catalitza la conversió de la glucosa-6-fosfat cap a fructosa 6-fosfat dins el segon pas de la glicòlisi . La variant humana d'aquest enzim es codifica pel gen GPI. flightservice engl
PHI (PHOSPHOHEXOSE ISOMERASE) TestingCancer.com
WebENZYME entry: EC 5.3.1.28 Accepted Name D-sedoheptulose-7-phosphate isomerase Alternative Name (s) phosphoheptose isomerase sedoheptulose-7-phosphate isomerase Reaction catalysed 2 D-sedoheptulose 7-phosphate <=> D-glycero-alpha-D-manno-heptose 7-phosphate + D-glycero-beta-D-manno-heptose 7-phosphate Comment (s) WebBackground: Glucose-6-phosphate isomerase (GPI) is a glycolytic-related enzyme that interconverts glucose-6-phosphate and fructose-6-phosphate in the cytoplasm. This protein is also secreted into the extracellular matrix by cancer cells and is, therefore, also called autocrine motility factor (AMF). WebFeb 3, 2016 · Sedoheptulose-7-phosphate isomerase, GmhA, is the first enzyme in the biosynthesis of nucleotide-activated-glycero-manno-heptoses and an attractive, yet underexploited, target for development of broad-spectrum antibiotics. We demonstrated that GmhA homologs in Neisseria gonorrhoeae and N ... Macromolecules flightservice-engl