TOPCAT is an interactive graphical viewer and editor for tabular data. Although a general purpose tool capable of handling large and sparse datasets with correlation functionality its specialist application area is astronomy and it was initially designed to support virtual observatories. It is able to handle several digital file formats including FITS which is in common use in astronomy. The Acronym TOPCAT derives from Tool for OPerations on Catalogues And Tables. WebThe primary outcome of the TOPCAT trial was a composite of cardiovascular mortality, aborted cardiac arrest, or heart failure hospitalization. Results: A total of 760 patients (43%) had a history of AF (18%) or AF on ECG at enrollment (25%). The highest adjusted risk was associated with AF at enrollment (primary outcome, hazard ratio: 1.34; 95% ...
Treatment of Preserved Cardiac Function Heart Failure With an ...
Web30. aug 2024 · Before any trial-related procedure is performed, the investigator will obtain informed consent from the study subject by means of a signed and dated informed consent approved by the local IRB/EC (or TOPCAT Central IRB) in his/her country. The informed consent process will be performed in accordance with the ICH guidelines (E6) for Good WebTOPCAT was a phase III, multicentre, international, randomized, double-blind, placebo-controlled trial. Patients were eligible if they were ≥50 years of age, exhibited at least one … gohermes.com
Lessons from the TOPCAT Trial NEJM
Web8. aug 2024 · The TOPCAT trial showed no benefit for spironolactone in heart failure patients with preserved ejection fraction (HFpEF). Post-hoc, spironolactone helped participants from the Americas, but not Eastern Europe. Determining which patients with HFpEF could respond like TOPCAT's responders should help guide their care. We aimed … Web12. jan 2024 · EP: 21. John McMurray, MBChB: One of the large trials conducted in patients with HFpEF [heart failure with preserved ejection fraction] was the TOPCAT trial, which enrolled just under 3500 ... Web10. apr 2014 · Lessons from the TOPCAT Trial. John J.V. McMurray, M.D., and Christopher O'Connor, M.D. Some patients with the clinical syndrome of heart failure have a normal or … go here now work from home